Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdh2  cadherin 2   (Synonyms: Ncad, N-CAD, N-cadherin)
Results	Reference
1	J:178696 Asami M, Pilz GA, Ninkovic J, Godinho L, Schroeder T, Huttner WB, Gotz M, The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex. Development. 2011 Dec;138(23):5067-78
1	J:273640 Camargo Ortega G, Falk S, Johansson PA, Peyre E, Broix L, Sahu SK, Hirst W, Schlichthaerle T, De Juan Romero C, Draganova K, Vinopal S, Chinnappa K, Gavranovic A, Karakaya T, Steininger T, Merl-Pham J, Feederle R, Shao W, Shi SH, Hauck SM, Jungmann R, Bradke F, Borrell V, Geerlof A, Reber S, Tiwari VK, Huttner WB, Wilsch-Brauninger M, Nguyen L, Gotz M, The centrosome protein AKNA regulates neurogenesis via microtubule organization. Nature. 2019 Mar;567(7746):113-117
1	J:194489 Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX, The wilms tumor gene, wt1, maintains testicular cord integrity by regulating the expression of col4a1 and col4a2. Biol Reprod. 2013;88(3):56
1*	J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27
1	J:263180 Dominguez Gonzalez B, Billion K, Rous S, Pavie B, Lange C, Goodchild R, Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease. Hum Mol Genet. 2018 Jun 15;27(12):2154-2170
1	J:236353 Dudok JJ, Murtaza M, Henrique Alves C, Rashbass P, Wijnholds J, Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon. Neurosci Res. 2016 Jul;108:12-23
1	J:320718 Duethorn B, Groll F, Rieger B, Drexler HCA, Brinkmann H, Kremer L, Stehling M, Borowski MT, Mildner K, Zeuschner D, Zernicka-Goetz M, Stemmler MP, Busch KB, Vaquerizas JM, Bedzhov I, Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism. Nat Commun. 2022 Feb 1;13(1):610
1*	J:228552 Ercan-Sencicek AG, Jambi S, Franjic D, Nishimura S, Li M, El-Fishawy P, Morgan TM, Sanders SJ, Bilguvar K, Suri M, Johnson MH, Gupta AR, Yuksel Z, Mane S, Grigorenko E, Picciotto M, Alberts AS, Gunel M, Sestan N, State MW, Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans. Eur J Hum Genet. 2015 Feb;23(2):165-72
1	J:201651 Gil-Sanz C, Franco SJ, Martinez-Garay I, Espinosa A, Harkins-Perry S, Muller U, Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues. Neuron. 2013 Aug 7;79(3):461-77
1*	J:180706 Gruber R, Zhou Z, Sukchev M, Joerss T, Frappart PO, Wang ZQ, MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway. Nat Cell Biol. 2011 Nov;13(11):1325-34
1	J:258793 Hayakawa-Yano Y, Suyama S, Nogami M, Yugami M, Koya I, Furukawa T, Zhou L, Abe M, Sakimura K, Takebayashi H, Nakanishi A, Okano H, Yano M, An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling. Genes Dev. 2017 Sep 15;31(18):1910-1925
1	J:294837 Huang C, Liu T, Wang Q, Hou W, Zhou C, Song Z, Shi YS, Gao X, Chen G, Yin Z, Hu Y, Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development. Cereb Cortex. 2020 Jun 1;30(7):4183-4196
1	J:163480 Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL, Semb H, N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover. Genesis. 2010 Jun;48(6):374-81
1	J:241995 Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien WH, Fernandez TE, Cooper JA, Vasioukhin V, Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells. Dev Cell. 2017 Jun 05;41(5):481-495.e5
1*	J:332214 Kaiser M, Ludtke TH, Deuper L, Rudat C, Christoffels VM, Kispert A, Trowe MO, TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti. Nat Commun. 2022 Dec 9;13(1):7628
1	J:306330 Le D, Lim S, Min KW, Park JW, Kim Y, Ha T, Moon KH, Wagner KU, Kim JW, Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity. Mol Cells. 2021 Mar 31;44(3):168-178
1*	J:238546 Li J, Liu Y, Jin Y, Wang R, Wang J, Lu S, VanBuren V, Dostal DE, Zhang SL, Peng X, Essential role of Cdc42 in cardiomyocyte proliferation and cell-cell adhesion during heart development. Dev Biol. 2017 Jan 15;421(2):271-283
1	J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134
1	J:204170 Luccardini C, Hennekinne L, Viou L, Yanagida M, Murakami F, Kessaris N, Ma X, Adelstein RS, Mege RM, Metin C, N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration. J Neurosci. 2013 Nov 13;33(46):18149-60
1	J:127463 Ma X, Bao J, Adelstein RS, Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell. 2007 Jun;18(6):2305-12
1*	J:213450 Machida A, Okuhara S, Harada K, Iseki S, Difference in apical and basal growth of the frontal bone primordium in Foxc1(ch/ch) mice. Congenit Anom (Kyoto). 2014 Aug;54(3):172-7
1*	J:135108 Manning JA, Colussi PA, Koblar SA, Kumar S, Nedd1 expression as a marker of dynamic centrosomal localization during mouse embryonic development. Histochem Cell Biol. 2008 Jun;129(6):751-64
1	J:235675 Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnar Z, Mueller U, Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 Jun 15;143(12):2121-34
1	J:339856 Ovadia S, Cui G, Elkon R, Cohen-Gulkar M, Zuk-Bar N, Tuoc T, Jing N, Ashery-Padan R, SWI/SNF complexes are required for retinal pigmented epithelium differentiation and for the inhibition of cell proliferation and neural differentiation programs. Development. 2023 Aug 15;150(16)
1*	J:41888 Packer AI, Elwell VA, Parnass JD, Knudsen KA, Wolgemuth DJ, N-cadherin protein distribution in normal embryos and in embryos carrying mutations in the homeobox gene Hoxa-4. Int J Dev Biol. 1997 Jun;41(3):459-68
1	J:234328 Perez Millan MI, Brinkmeier ML, Mortensen AH, Camper SA, PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells. Elife. 2016;5:e14470
1	J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109
1	J:244798 Recuenco MC, Ohmori T, Tanigawa S, Taguchi A, Fujimura S, Conti MA, Wei Q, Kiyonari H, Abe T, Adelstein RS, Nishinakamura R, Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons. J Am Soc Nephrol. 2015 May;26(5):1081-91
1	J:149456 Rocha SF, Lopes SS, Gossler A, Henrique D, Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol. 2009 Apr 1;328(1):54-65
1	J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13
1	J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35
1	J:163275 Snyder EM, Small CL, Bomgardner D, Xu B, Evanoff R, Griswold MD, Hinton BT, Gene expression in the efferent ducts, epididymis, and vas deferens during embryonic development of the mouse. Dev Dyn. 2010 Sep;239(9):2479-91
1*	J:297657 Song J, Ding W, Liu Y, Lin L, Jia M, Liu S, Xue K, The mesenchymal property of mouse mammary anlagen repopulating cell population is associated with its stemness. Gene Expr Patterns. 2020 Dec;38:119151
1	J:332432 Sterling NA, Park JY, Park R, Cho SH, Kim S, An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis. Nat Commun. 2023 Jan 5;14(1):82
1	J:167033 Sugiyama Y, Koike T, Shiojiri N, Developmental changes of cell adhesion molecule expression in the fetal mouse liver. Anat Rec (Hoboken). 2010 Oct;293(10):1698-710
1	J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5
1	J:98470 Teng J, Rai T, Tanaka Y, Takei Y, Nakata T, Hirasawa M, Kulkarni AB, Hirokawa N, The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. Nat Cell Biol. 2005 May;7(5):474-82
1	J:306109 Thomas K, Henley T, Rossi S, Costello MJ, Polacheck W, Griffith BE, Bressan M, Adherens junction engagement regulates functional patterning of the cardiac pacemaker cell lineage. Dev Cell. 2021 May 17;56(10):1498-1511.e7
1	J:269956 Wada K, Matsushima Y, Tada T, Hasegawa S, Obara Y, Yoshizawa Y, Takahashi G, Hiai H, Shimanuki M, Suzuki S, Saitou J, Yamamoto N, Ichikawa M, Watanabe K, Kikkawa Y, Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice. PLoS One. 2014;9(10):e111432
1	J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52
1	J:229121 Yamamoto H, Mandai K, Konno D, Maruo T, Matsuzaki F, Takai Y, Impairment of radial glial scaffold-dependent neuronal migration and formation of double cortex by genetic ablation of afadin. Brain Res. 2015 Sep 16;1620:139-52
1	J:276051 Zhang T, Zhang S, Song X, Zhao X, Hou C, Li Z, Gao J, Loss of Lgl1 Disrupts the Radial Glial Fiber-guided Cortical Neuronal Migration and Causes Subcortical Band Heterotopia in Mice. Neuroscience. 2019 Feb 21;400:132-145